BONE DISEASE

any of the diseases and injuries that affect human bones. Diseases and injuries of bones are major causes of abnormalities of the locomotor system. Although physical injury, causing fracture, dominates over disease, fracture is but one of several common causes of bone disease, and disease, in fact, is a common cause of fracture. Bone diseases and injuries were formerly regarded as conditions that were more mechanical than metabolic. An improved understanding of the dual mechanical and chemical function of bone, however, has permitted a more integrated biological view. Additional reading R.B. Salter, Textbook of Disorders and Injuries of the Musculoskeletal System (1970), a comprehensive modern text dealing with aspects of orthopedics, rheumatology, metabolic bone disease, rehabilitation, and fractures as they relate to joint diseases, including bibliographies in each subsection; W.J.W. Sharrard, Paediatric Orthopaedics and Fractures (1971), a comprehensive textbook written by a specialist in neurological and developmental abnormalities in children; E.E. Aegerter and J.A. Kirkpatrick, Jr., Orthopaedic Diseases: Physiology, Pathology, Radiology, 3rd ed. (1968), a standard text on bone pathology, particularly tumour pathology; L. Lichtenstein, Diseases of Bones and Joints (1970), a modern text on nontumorous diseases; and A.H. Crenshaw (ed.), Campbell's Operative Orthopaedics, 5th ed., 2 vol. (1971), a standard text on bone and joint surgery. C.L. Berry (ed.), Bone and Joint Diseases (1982), is a text on the diagnosis of bone disease. For a visual approach, see Victor Parsons and George Stirling, Color Atlas of Bone Disease (1980).