PARA-AMINOSALICYLIC ACID

(PAS) also called aminosalicylic acid chemotherapeutic drug used in combination with isoniazid or the antibiotic streptomycin to treat tuberculosis. Para-aminosalicylic acid (PAS), which is administered orally, is only slightly antituberculotic when used alone. It was introduced in the treatment of tuberculosis in 1946. The use of para-aminosalicylic acid in combination with isoniazid or streptomycin helps reduce or delay the development of resistant strains of the tubercle bacillus.