noun
1.
Synonyms: sorrow , affliction, anguish, ||dole, grief, heartache, heartbreak, regret, rue, woe
Related Word: strain, stress, tension
2.
a burdened or disquieted state of mind
a mind full of care and sadness
Synonyms: anxiety, concern, concernment, disquiet, disquietude, solicitude, unease, uneasiness, worry
Related Word: apprehension, foreboding, misgiving, suspense; agitation, disturbance, perturbation; alarm, consternation, dismay, fear
Contrasted words: calm, ease, peace, quietude; assurance, comfort, easiness
3.
Synonyms: trial 2, trouble, worry
4.
serious and heedful attentiveness
attended his words with care
Synonyms: carefulness, concern, consciousness, heed, heedfulness, regard; compare attention 1
Related Word: curiosity; enthusiasm, interest; consideration, solicitude, thoughtfulness; effort, exertion, pains, trouble; alertness, vigilance, watchfulness
Contrasted words: carelessness, disregard, heedlessness, unconcern; boredom, disinterest, ennui
5.
Synonyms: oversight 1, charge, conduct, handling, intendance, management, running, superintendence, superintendency, supervision
6.
Synonyms: custody , guardianship, keeping, safekeeping, trust, ward