1.
If you ~ something that is restricting you or making you unhappy, you get rid of it.
...a country ready to ~ the shackles of its colonial past...
One day depression descended upon him, and wherever he went after that he could never throw it off.
= cast off
PHRASAL VERB: V P n (not pron), V n P
2.
If something throws off a substance, it produces it and releases it into the air.
The belt may make a squealing noise and ~ sooty black particles of rubber...
= give off
PHRASAL VERB: V P n (not pron)
3.
If you ~ people who are chasing you or trying to find you, you do something unexpected that makes them unable to catch you or find you.
He is said to have thrown off pursuers by pedaling across the Wisconsin state line...
He tried to throw police off the track of his lover.
PHRASAL VERB: V P n (not pron), V n P n, also V n P