I. noun
COLLOCATIONS FROM OTHER ENTRIES
a dose of poison (= an amount of poison )
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He had taken a massive dose of poison.
a dose of radiation (= an amount of radiation that someone experiences )
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Workers at the site received high doses of radiation.
a dose of reality (= an experience of what things are really like )
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I got my first dose of reality when I reported to work at my new job.
lethal dose
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a lethal dose of heroin
COLLOCATIONS FROM CORPUS
■ ADJECTIVE
fatal
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Digitalis, a heart drug that can be fatal in higher doses , is derived from the foxglove plant.
healthy
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A healthy dose of realism does no harm here.
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Chrys Chrys recommends a healthy dose of fresh lemon juice squeezed over the fish.
heavy
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But given heavy doses of baking soda he began to recover, and was perfectly normal three days later.
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Aristotle answered: by inducing heavy doses of pity and terror.
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As a result, a heavy dose of reality has descended on the Buchanan campaign.
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Of course, tolerance to very heavy doses of caffeine may be problematic for health reasons.
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I can't help feeling, therefore, that your critical position relies on a heavy dose of bad faith.
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C., a heavy dose of reality is setting in.
high
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In the rat, very high single doses of intravenous mesalazine cause acute tubular and papillary necrosis.
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Some side effects of high doses include acne, oily skin and insomnia.
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It is also true that such high doses have no place in ordinary maintenance drug regimes.
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However, the risk of damage for heavier drinkers becomes severe when higher doses of acetaminophen are taken.
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Either lower or higher doses are then injected serially until the weal or the symptoms disappear.
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The quick, new, high-dose radiation Brachytherapy for cancer patients is also performed at the hospital.
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So small volumes of lung tissue are exposed to high doses of alpha radiation.
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Most of the psychotic episodes experienced by people using Halcion involved high doses for extended periods of time.
large
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In small amounts it can act as a stimulant, in larger doses causing hyperactivity, headaches and insomnia.
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In large doses it can cause nausea, vomiting, difficulty breathing and coma.
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But most cancers failed to respond at all to the largest doses which were tolerated by healthy tissues.
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About that proposition, a large dose of skepticism is in order.
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Both single large doses and fractionated doses of radiation have been shown to alter small intestinal motility in animals.
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Advocates say that large doses of antioxidants protect against cancer by soaking up dangerous oxygen molecules that can damage cells.
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In very large doses they cause stimulation of the central nervous system, convulsions and death.
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Such aggregations not only promote transmission of micro-organisms but through repeated exposure allow large doses of these.
lethal
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Operators received lethal doses of radiation while needlessly reconnecting the water supply to the devastated reactor.
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The prison staff member will then begin to administer lethal doses of three chemicals.
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Some workers received lethal doses because the rest of the site was not evacuated.
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What effect on pain might, say, three-quarters of the lethal dose have had?
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Usually one of Robert's business prospects would be invited for a lethal dose of glamour.
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The river still carries a lethal dose of poisons.
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Shipman was convicted last year of murdering 15 female patients with lethal doses of diamorphine.
low
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Astra refuses to conduct further rat studies with lower doses of ranitidine, saying that this is Glaxo's job.
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In low doses , ephedrine speeds up the body, causing restlessness, insomnia, and nervousness.
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Either lower or higher doses are then injected serially until the weal or the symptoms disappear.
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Another favorable characteristic is that there is a rapid build-up of serum levels, even when starting at low doses .
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But they had no low dose folic acid supplements.
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Those on moderate or low doses of inhaled steroids showed no increased risk of glaucoma or ocular hypertension.
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Generally, lower doses are used than in organ transplantation.
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At low to moderate doses , these drugs significantly reduce anxiety without impairing or disrupting other brain systems.
massive
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I stayed at home as much as possible while I took massive doses of testosterone, the male hormone.
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The most outrageous examples involve force-feeding massive doses of sugar substitutes to white laboratory mice, who eventually grew tumors.
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In massive dose , however, 4-ASA may cause haematuria and reduce creatinine clearance, particularly in patients with pre-existing renal disease.
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He said he has not been convince d that such a massive dose has much value.
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But then the truth about the massive doses of poison which Allitt administered to those babies in her care was uncovered.
mild
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It will make the Black Death look like a mild dose of flu.
safe
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If there is no safe dose cancer rates should increase as the natural background radiation level increases.
single
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In the rat, very high single doses of intravenous mesalazine cause acute tubular and papillary necrosis.
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Both single large doses and fractionated doses of radiation have been shown to alter small intestinal motility in animals.
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But simpler forms of the drugs, including pills combining more than one drug in a single dose , are becoming available.
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Apart from the single ecstasy dose , she believed she had drunk only a glass of wine that night.
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In contrast, Rijk etal evaluated the faecal excretions of healthy volunteers with accelerated transit time after a single dose .
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The authors claim that single dose treatment has not yet been proved adequate in this context.
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There was the high potency, single dose , classical Kentian school, and the low potency, often-repeated school of Hughes.
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This shows the insensitivity of single dose comparisons as a method of estimating relative potency.
small
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Many of these schemes have been tried before in small doses .
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Hence patients requiring smaller doses of levodopa who are troubled with nausea cardiac arrhythmias, or hypotension may use this dosage form.
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This can be infectious in small doses , and her catchy anthem, Finally, is pop at its most celebratory.
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Life is simple and quiet out here, and even small doses can purify you.
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Knock! jokes are okay in small doses - like one every second leap year.
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For these individuals the drug must be divided into four or five smaller doses per day.
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Problems with diamorphine include vomiting, bradycardia, and hypotension, but in small doses diamorphine is better than any sedative.
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Some local attorneys worry about short-term privacy lapses and long-term effects of even small radioactive doses .
standard
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In this study, a standard bone sparing dose of oral oestrogen was used.
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In contrast, the standard dose of alcohol is measured in liquid ounces.
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The standard dose of alcohol is thus roughly 142 times larger than the standard dose of caffeine.
strong
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A very strong dose of moral medicine indeed.
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The group support offered in diet programs, though, has usually been mixed with a strong dose of group humiliation.
■ VERB
administer
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The prison staff member will then begin to administer lethal doses of three chemicals.
give
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She was given a dose of Hyper. 30 from her first-aid kit and sent to the neurologist.
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So when Casey started public school, first grade, the school nurse had to give him his second dose .
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They were given three large doses of vitamin A over a week, and received vitamin A in all subsequent survey rounds.
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One tablet or ten tablets taken as one dose still only gives one dose of the potency, does it not?
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Aminoglycosides are often given in insufficiently high doses .
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Miss T. was given another dose of pethidine.
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But some people are allergic to even this highly-purified animal collagen, so potential recipients are first given a small test dose .
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A little arsenic can cure disorders of the stomach, but given in regular small doses becomes a poison.
increase
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A dose response to oestrogens has been shown with increasing doses having greater effects on bone density.
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Many habitual drinkers of caffeine-containing beverages find that they must increase their dose to achieve the preferred degree of stimulation.
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Analgesics were given in increasing doses and ascending potency until pain was controlled.
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Tolerance means that with regular use, you need to increase the dose to achieve the same effect.
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If you are using undergravel filters you will need to increase the dose by 50%.
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It is more generally understood as pain that is made worse rather than better by increasing doses of morphine.
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In the present study the addition of increasing doses of egg lecithin to human and model biles progressively prolongs the nucleation time.
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Biliary lipid composition was not altered significantly but bicarbonate output was increased at all doses tested.
reduce
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Thorough revision of laboratory routines could substantially reduce radiation doses received.
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In all instances the toxicity was easily reversed by reducing the cyclosporin dose .
require
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Repetition of the remedy is continued for as long as is required , and the doses are tailed off gradually.
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Hence patients requiring smaller doses of levodopa who are troubled with nausea cardiac arrhythmias, or hypotension may use this dosage form.
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Effective analgesia should be administered; the pain is often severe enough to require high dose of morphine or pethidine.
take
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One tablet or ten tablets taken as one dose still only gives one dose of the potency, does it not?
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The time it takes for a dose of a drug to wear off is measured by a value called a half-life.
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Or will he be brave enough to take a dose of poison at the last moment?
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She is taking the same dose of medicine that she had received at the hospital.
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Plasma concentrations of 5-ASA may therefore be higher in patients taking delayed release mesalazine than in patients taking equivalent doses of sulphasalazine.
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Many are taking several times the dose recommended.
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I knew she had taken a fine dose .
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This time I had to take a double dose to return to my old shape.
use
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The necessity for using very high doses of reagents, however, to detect invitro phosphorylation of membranes, is well recognised.
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Most of the psychotic episodes experienced by people using Halcion involved high doses for extended periods of time.
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If two injections are required, attempting to use the same dose morning and evening may be helpful.
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Be sure you are using the appropriate dose however.
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Damage to living tissue can be quantified by using the dose equivalent.
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If a pesticide has to be used , a smaller dose may be adequate.
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Discussion Ascorbic acid has been used in pharmacological doses for more than 20 years.
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Transit times were determined using a multiple dose marker technique.
PHRASES FROM OTHER ENTRIES
give sb a dose/taste of their own medicine
EXAMPLES FROM OTHER ENTRIES
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The banks need a healthy dose of competition.
EXAMPLES FROM CORPUS
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A dose of old-fashioned repression dealt with some of the bold exceptions.
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About that proposition, a large dose of skepticism is in order.
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Finding such a dose response would have made the case stronger.
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She was given a dose of Hyper. 30 from her first-aid kit and sent to the neurologist.
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The Cosbys are getting a dose of what families of homicide and fatal accident victims get routinely.
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The designation was made because at high doses, alcohol slows down the central nervous system.
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The laxative dose required to treat constipation in the young child is much higher than the suggested doses on the label.
II. verb
EXAMPLES FROM CORPUS
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Elsie and Edith Port were so alike that Jennie dosed the wrong one with her cure for all ailments - castor oil.
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It is generally price advantageous to specify powders although in use they may be more difficult to control and dose .
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When the children were ill, she dosed them with herb teas that she brewed herself.