BLOT

I. noun Etymology: Middle English Date: 14th century a soiling or disfiguring mark ; spot , a mark of reproach ; moral flaw, a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (as a complementary nucleic acid or a radio labeled antibody), II. verb (~ted; ~ting) Date: 15th century transitive verb to spot, stain, or spatter with a discoloring substance, mar , 3. to dry (as writing) with an absorbing agent, to remove with absorbing material , intransitive verb to make a ~, to become marked with a ~, III. noun Etymology: perhaps from Dutch bloot naked, exposed, from Middle Dutch; akin to Middle High German bloz bare Date: 1595 a lone backgammon man exposed to capture, a weak or exposed point