ˌlükō¦trī¦ēn noun
( -s )
Etymology: leuko cyte + -triene ; from the discovery of the substances in leukocytes
: any of a group of eicosanoids that are generated in basophils, mast cells, macrophages, and human lung tissue by lipoxygenase-catalyzed oxygenation especially of arachidonic acid and that participate in allergic responses (as bronchoconstriction in asthma)