DE PROFUNDIS Meaning of DE PROFUNDIS in English [ ˌdeɪ prə'fʊndɪs ]■ adverb expressing one's deepest feelings. ■ noun a heartfelt appeal.OriginL., 'from the depths', the opening words of Psalm 130. Concise Oxford English vocab. Сжатый оксфордский словарь английского языка. 2004