noun
BAD : The signature of the new protocol took place in Rio de Janeiro.
GOOD : The signing of the new protocol took place in Rio de Janeiro.
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signature = your name, written in the way that you usually write it on a cheque, business letter etc: 'These letters need your signature, Mr Ross.' 'You can tell by the signature if the painting is genuine.'
To refer to the event at which two or more people sign a legal or formal agreement, use signing : 'The signing of the peace agreement is scheduled to take place in Zurich at the end of the month.'