FACTOR VIII

A coagulation (clotting) factor. Classic hemophilia (hemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic hemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be hemophiliacs.