TWENTY-TWO Meaning of TWENTY-TWO in English [twen.ty-two] n (1526) 1: two more than twenty 2: a .22-caliber firearm; esp: one firing rimfire cartridges--usu. written .22 -- twenty-two adj -- twenty-two pron, pl in constr Merriam-Webster English vocab. Английский словарь Merriam Webster. 2012