Phrs. Said of a person who is unsettled and is unable remain seated and still. Numerous variations exist, i.e. whore may be replaced by prostitute, or tart, and knickers with pants etc..
UP AND DOWN LIKE A WHORE'S KNICKERS
Meaning of UP AND DOWN LIKE A WHORE'S KNICKERS in English
Slang English vocab. Английский сленговый словарь. 2012