v. phr. To do the most you can with; get the most from; use to the greatest advantage. She planned the weekend in town to make the most of it. George studied hard. He wanted to make the most of his chance to learn. The teacher went out of the room for five minutes and some bad boys made the most of it. Bill liked Mary; he would do anything for her, and Mary made the most of it.
Compare: MAKE HAY WHILE THE SUN SHINES.