{v. phr.} 1. To shoot yourself in the head. * /Mr. Jones lost all his wealth, so he blew his brains out./ 2. {slang} To work very hard; overwork yourself. * /The boys blew their brains out to get the stage ready for the play./ * /Mary is not one to blow her brains out./ Compare: BREAK ONE'S NECK.
BLOW ONE'S BRAINS OUT
Meaning of BLOW ONE'S BRAINS OUT in English
Slang English vocab. Английский сленговый словарь. 2012