{v. phr.}, {informal} To work very hard; make a great effort. * /Mrs. Ross knocked herself out planning her daughter's wedding./ * /Tom knocked himself out to give his guests a good time./ Compare: BREAK ONE'S NECK, FALL OVER BACKWARDS, OUT OF ONE'S WAY.
KNOCK ONESELF OUT
Meaning of KNOCK ONESELF OUT in English
Slang English vocab. Английский сленговый словарь. 2012