Little Miss Muf ‧ fet /ˌlɪtl mɪs ˈmʌfət/ BrE AmE
a character from a ↑ nursery rhyme (=an old song or poem for young children) . She is a young girl who is frightened by a ↑ spider and runs away:
Little Miss Muffet/Sat on a tuffet,/Eating her curds and whey;/There came a great spider,/Who sat down beside her,/And frightened Miss Muffet away.